A method for a slow-release of drugs from orally dissolving capsule has been described. It releases medicaments in the mouth cavity up to 1 hour. The medicaments may have a therapeutic effect in the mouth cavity and a portion of the drug is delivered to stomach. Thus, the medication may have a local action in the oral cavity and/or have a systemic effect. Mainly, the orally dissolving capsule is administered without an aid of water. Also, large capsules such as size “000” can be administered allowing delivery of large amounts (800 to 1600 mg) of medicament. The medicament can be absorbed through mouth cavity (oral transmucosal absorption) to blood stream bypassing hepatic first pass metabolism. In some instances, a drug(s) is incorporated in the ODC empty shell matrix and no drug composition is filled inside the capsule shell core.
