Sean H. Kevlahan,Andrew Ball,Guokui Qin,Steven B. Wells,Nithya Jothi Jesuraj,Julie M. Cole
申请号：
US16494197
公开号：
US20200085971A1
申请日:
2018.03.20
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention features a hydrogel complex that can bind to and modulate a desired immune cell, e.g., T cell, population. In certain embodiments, the complex can be dissolved, and thus dissociated from its targeted cell, representing a safe and efficient approach for processing immune cells, e.g., T cells for clinical use. The invention also provides methods and apparatus for synthesizing hydrogel complexes, as well as methods of using the complexes to generate expanded immune cell, e.g., T cell, populations as part of adoptive immune cell, e.g., T cell, therapy systems.
