The invention relates to compounds of theformula Ihaving antithrombotic activity, which in particular inhibit the protease-activated receptor 1 (PAR1), processes for their preparation and use thereof as medicaments.本發明關於具有抗血栓阻塞活性之具式I之化合物,特別是用於抑制蛋白酶-活化的受體1(PAR1):也關於製備彼等之方法以及以彼等作為醫藥品之用途。