An oral care implement with a gripping portion. The oral care implement is a toothbrush (100) including an elongated body (101) formed of a first material and a handle (104) including a proximal gripping portion (114) and a distal neck portion (115) supporting a head (102) containing a plurality of tooth cleaning elements (108). A longitudinally elongated through slot (130) is formed in the gripping portion (114) of the handle (104) which extends transversely between front and rear exposed surfaces (112) of the handle (104). A second material which is elastomeric is disposed in the slot (130). A longitudinally elongated depression (120) having a transversely concave profile is formed in the rear exposed surfaces (112) of the handle (104) which communicates with the slot (130). The second material extends at least partially in the depression (120).
