monomeric vhh domain derived from anti-camelid vp6 antibodies, dimeric domain, immunization method, rotavirus detection method, composition, methods of preventing and treating rotavirus infections.

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专利权人:

INSTITUTO NACIONAL DE TECNOLOGIA AGROPECUARIA (INTA);ALTERNATIVE GENE EXPRESSION, S.L.(ALGENEX)

发明人:

ANDRÉS WIGDOROVITZ,AURELIEN OLICHON,GISELA ARIANA MARCOPPIDO,GLADYS VIVIANA PARREÑO,JOSÉ ANGEL MARTÍNEZ ESCRIBANO,LORENA LAURA GARAICOEACHEA,SILVIA GÓMEZ SEBASTIÁN,THOMAS SURREY

申请号：

BRPI0815763

公开号：

BRPI0815763A2

申请日:

2008.07.24

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

Monomeric VHH domain derived from anti-VP6 camelid antibodies, dimeric domain, immunization method, rotavirus detection method, vaccine composition, prevention and treatment methods for rotavirus infections, wherein said domain may be any of the amino acid sequences shown in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 or SEQ ID No. 4, and wherein said domains bind to protein VP6 of Group A rotavirus.

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