Ronald James Jackson,Ian Allister Ramshaw,Charani Ranasinghe
申请号:
US13381757
公开号:
US20120177668A1
申请日:
2010.07.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention relates generally to compositions and methods for modulating immune responses. More particularly, the present invention relates to the co-expression, co-location or co-presentation on host cells (e.g. antigen-presenting cells, leukocytes, etc) of an inhibitor of IL-13 function and an immune stimulator that stimulates an immune response to a target antigen in compositions and methods for stimulating protective or therapeutic immune responses to the target antigen. The compositions and methods of the present invention are particularly useful in the prophylaxis and/or treatment of a range of diseases or conditions including pathogenic infections and cancers.