DOMINGUEZ, CELIA,MUN~OZ-SANJUAN, IGNACIO,LUCKHURST, CHRISTOPHER A.,ALLEN, DANIEL R.,RAPHY, GILLES,BURLI, ROLAND W.,BRECCIA, PERLA,HAUGHAN, ALAN F.,WISHART, GRANT,HUGHES, SAMANTAH J.,JARVIS, REBECCA E.
申请号:
CA2951026
公开号:
CA2951026A1
申请日:
2015.06.01
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.