Academic Hospital Maastricht;Maastricht University
发明人:
Peter Joseph Emans,Lodewijk Willem Van Rhijn,Tim Johannes Maria Welting,Mike De Leeuw
申请号：
US13677071
公开号：
US20130123314A1
申请日:
2012.11.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention is in the field of methods for medical treatment. It provides an improved method for repairing damaged cartilage and/or preventing cartilage degeneration in tissue, in particular in a joint by administering a pharmaceutically active agent directly into the fat pad of a joint. The pharmaceutically active agent is preferably selected from the group consisting of agents that stimulate chondrogenic differentiation and/or cartilage matrix synthesis； agents that inhibit osteogenesis and/or hypertrophy, anti-inflammatory agents, agents that inhibit apoptosis of chondrocytes, agents that inhibit senescence of chondrocytes and agents that enhance lubrication of a joint.
