Apparatuses, systems, methods, and program products are disclosed for targeted electrical stimulation. A method includes determining, by a processor, a base configuration for each of a plurality of electrodes configured to transmit an electrical current towards a target area of a biological structure. A method includes calculating a cost associated with transmitting an electrical current to the target area according to the base configuration. A method includes modifying the base configuration in response to the calculated cost not satisfying a minimum cost threshold. The modified configuration clusters electrical current transmitted by each of the electrodes at the target area according to a resistivity map of the biological structure to minimize the cost of transmitting the electrical current. The cost is re-calculated according to the modified configuration and the configuration is modified until the minimum cost threshold is satisfied. A method includes graphically presenting the configuration for each of the electrodes.
