BIOMARKERS FOR INFLAMMATORY DISEASE AND METHODS OF USING SAME

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专利权人:

发明人:

Carolyn Cuff,Melanie C. Ruzek,Jeffrey W. Voss

申请号：

US14736256

公开号：

US20160000936A1

申请日:

2015.06.10

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The invention provides methods for predicting the efficacy of anti-TNF and anti-IL-17 combination therapies in the treatment of a subject suffering from inflammatory disease by determining the level LIF, CXCL1, CXCL2, CXCL4, CXCL5, CXCL8, CXCL9, CXCL10, CCL2, CCL23, IL-1β, IL-1Ra, TNF, IL-6, IL-10, IL-17A, IL-17F, IL-21, IL-22, IFNγ, CXCR1, CXCR4, CXCR5, GM-CSF, GM-CSFR, G-CSF, G-CSFR protein or nucleic acid, or a homolog, portion or derivative thereof markers in a sample derived from the subject.

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