Sergei Zolotukhin,Sean M. Crosson,Cedrick Shawn Dotson,Seth Currlin
申请号：
US15489717
公开号：
US20170326257A1
申请日:
2017.04.17
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present application provides methods and compositions for AAV-mediated delivery of PYY and Glucagon-like Peptide 1 or an analog thereof (e.g., Exendin-4) to a subject (e.g., the saliva of a subject). In some embodiments, compositions and methods for topical delivery of Ex-4 and PYY peptides also are provided. Methods and compositions are useful to promote weight loss and/or altered lipid taste sensitivity, as well as for the treatment of diabetes.
