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TRIPEPTIDES DIFLUORÉS EN TANT QU'INHIBITEURS DE LA SÉRINE PROTÉASE DU VHC
专利权人:
INC.;ENANTA PHARMACEUTICALS
发明人:
GAI, YONGHUA,OR, YAT, SUN,WANG, ZHE
申请号:
EP09704258
公开号:
EP2245015A4
申请日:
2009.01.22
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis c virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis c virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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