Lipid constructs for delivering insulin to mammals

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专利权人:

エスデイージー・インコーポレーテツド

发明人:

ラウ，ジヨン・アール,ジエホ，ダブリユー・ブレア,ラウ,ジヨン・アール,ジエホ,ダブリユー・ブレア

申请号：

JP2008513541

公开号：

JP5414270B2

申请日:

2006.05.16

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The instant invention is drawn to a hepatocyte targeted composition comprising interferon associated with a lipid construct comprising amphipathic lipid molecules and receptor binding molecule. The composition can comprise a mixture of free interferon and interferon associated with the complex. The composition can be modified to protect interferon and the complex from degradation. The invention also includes methods for the manufacture of the composition and loading interferon into the composition and recycling various components of the composition and methods of treating individuals infected with the hepatitis C and other hepatitis viruses.

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