Steve Shih-Lin Huang,Warren D. Heston,Xinning Wang
申请号：
US15632527
公开号：
US20170354748A1
申请日:
2017.06.26
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A PSMA-specific imaging agent comprising a compound according to formula I:are described, wherein S1 is an organic spacer group having from 5 to 30 carbons, A is an amino acid forming a portion of a negatively charged peptide oligomer, n is from 3 to 6, S2 is an organic spacer group having from 5 to 15 carbons, and I is an imaging group, and pharmaceutically acceptable salts thereof. The PSMA-specific imaging agents can be used to image PSMA within a tissue region to guide the treatment of diseases such as prostate cancer.
