Isoquinolone derivatives substituted with warm piperidinilo inhibitors of Rho kinase

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专利权人:

SANOFI

发明人:

Kadereit, Dieter,Hofmeister, Armin,Plettenburg, Oliver,Brendel, Joachim,Loehn, Matthias

申请号：

NO20080963

公开号：

NO341888B1

申请日:

2008.02.22

申请国别(地区):

NO

年份:

2018

代理人:

摘要：

The present Invention relates to novel isoquinoline isoquinolone derivatives I, their Preparation and their use in the treatment and / or prevention of diseases related to inhibition of Rho Kinase and / or the Rho kinase mediated phosphorylation of the phosphatase of light chain d And Myosin.Foreliggende oppfinnelse angår 6-piperidinylsubstituerte isoquinolonderivater med formel (I) eller isoquinolinderivater med formel (I') anvendelige for behandling og/eller hindring av sykdommer assosiert med Rho-kinase og/eller Rho-kinasemediert fosforylering av myosinlettkjedefosfatase, og sammensetninger som inneholder slike forbindelser.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/