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TEXAPHYRIN-PT(IV) CONJUGATES AND COMPOSITIONS FOR USE IN OVERCOMING PLATINUM RESISTANCE
专利权人:
BOARD OF REGENTS; THE UNIVERSITY OF TEXAS SYSTEM
发明人:
Jonathan L. SESSLER,Jonathan ARAMBULA,Zahid H. SIDDIK,Gregory THIABAUD
申请号:
US16563714
公开号:
US20200069698A1
申请日:
2019.09.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.
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