A tomographic image generation device that generates a tomographic image by using a transmitting and receiving unit in which an ultrasonic wave transmitting and receiving unit that performs ultrasonic wave transmission and reception and an optical transmitting and receiving unit that performs light transmission and reception are disposed acquires ultrasonic wave data and interference light data to be used for generating a tomographic image for one line in respective rotation positions of the transmitting and receiving unit by performing sampling respectively on an ultrasonic wave echo signal and an interference light signal obtained by driving the ultrasonic wave transmitting and receiving unit and the optical transmitting and receiving unit while rotating the transmitting and receiving unit. Then, the tomographic image generation device controls operation timing of the acquisition means so that a sampling period for performing sampling on the interference light signal for 1 line and a predetermined period from driving of the ultrasonic wave transmitting and receiving unit for ultrasonic wave oscillation are not overlapped.
