Ta-Jo Liu,Hsiu-Feng Yeh,Yu-Sheng Lin,Yun-Hsuan Chen,Hung-Hsing Lin
申请号：
US16698875
公开号：
US10793701B1
申请日:
2019.11.27
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a base composition for a microneedle patch and a microneedle patch comprising the same. The base composition comprises a first HPMC, a second HPMC and PVP/VA, wherein the viscosity of the first HPMC is greater than that of the second HPMC, the weight ratio of the first HPMC relative to the second HPMC is 1:0.1 to 1:1.2, and the amount of the PVP/VA is 0.25 wt % to 2 wt %. By controlling the constitution of the base composition, the microneedle patch can not only be demolded smoothly during the stage of the production, but also obtain the desired softness, flatness, flexibility, skin adhesion during the stage of use and humidity resistance during the stage of storage.
