JOHNS, BRIAN ALVIN,KAWASUJI, TAKASHI,TAISHI, TERUHIKO,TAODA, YOSHIYUKI
申请号：
MYPI 20071883
公开号：
MY149571A
申请日:
2007.10.31
申请国别(地区):
MY
年份:
2013
代理人:
摘要：
THE PRESENT INVENTION IS TO PROVIDE A NOVEL COMPOUND (I), HAVING THE ANTI-VIRUS ACTIVITY, PARTICULARLY THE HIV INTEGRASE INHIBITORY ACTIVITY, AND A DRUG CONTAINING THE SAME, PARTICULARLY AN ANTI-HIV DRUG, AS WELL AS A PROCESS AND AN INTERMEDIATE THEREOF. WHEREIN Z¹ IS NR⁴ R¹ IS HYDROGEN OR LOWER ALKYL X IS A SINGLE BOND, A HETERO ATOM GROUP SELECTED FROM O, S, SO, SO2 AND NH, OR LOWER ALKYLENE OR LOWER ALKENYLENE IN WHICH THE HETERO ATOM GROUP MAY INTERVENE R² IS OPTIONALLY SUBSTITUTED ARYL R³ IS HYDROGEN, A HALOGEN, HYDROXY, OPTIONALLY SUBSTITUTED LOWER ALKYL ETC AND R⁴ AND Z² PART TAKEN TOGETHER FORMS A RING, TO FORM A POLYCYCLIC COMPOUND, INCLUDING E.G., A TRICYCLIC OR TETRACYCLIC COMPOUND.
