The invention relates to a pharmaceutical composition comprising a mixture of at least one cationic, water-soluble (meth)acrylate copolymer, at least one water-insoluble polymer and at least one active ingredient having a solubility in demineralized water of 3.3 g/l or less, characterized in that the water-insoluble polymer and the active ingredient are present in a ratio of at most 3.5 to 1 parts by weight, and the pharmaceutical composition has the property of releasing the active ingredient present in a medium buffered to pH 1.2 in dissolved form in a concentration which, after 2 hours at pH 1.2, corresponds to at least sixteen times the solubility value of the active ingredient alone at pH 1.2.本發明係關於一種藥學組成物，其包含由至少一種陽離子、水溶性(甲基)丙烯酸酯共聚物，至少一種水不溶性聚合物和至少一種在去礦質水中具有3.3克/升或更低的溶解度的活性成份所成之混合物，且其特徵在於該水不溶性聚合物和該活性成份係以最多3.5對1重量份的比例存在，且該藥學組成物具有下述性質：其可將所含活性成份以溶解形式釋放到經緩衝至pH 1.2的介質內，使其濃度在pH 1.2下經2小時之後，相當於該活性成份單獨在pH 1.2的溶解度值之至少16倍。
