COMPOSITIONS ET PROCEDES D'UTILISATION DE L'INTERLEUKINE-10 EN ASSOCIATION AVEC DES INHIBITEURS DE VOIES DE POINTS DE CONTROLE IMMUNITAIRE

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专利权人:

INC.;ARMO BIOSCIENCES

发明人:

OFT, MARTIN

申请号：

CA3079844

公开号：

CA3079844A1

申请日:

2018.11.02

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present disclosure provides a method for the treatment of neoplastic disease in a mammalian subject the method comprising the administration of an IL-10 agent in combination with the administration of at least one modulator of at least one immune checkpoint pathway. The present disclosure further provides a method for the treatment of neoplastic disease wherein the neoplasm has a low or intermediate tumor mutation burden, low or intermediate level of expression of the immune checkpoint molecule, or metastatic neoplastic disease.

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