Jo KLAVENESS,Bora SIENG,Steffi LUNDVALL,Claudia Alejandra BØEN,Kathrin HNIDA
申请号:
US16613837
公开号:
US20200165233A1
申请日:
2018.05.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention provides compounds of formula (I), stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof: (I) wherein A1 to A6 and R1 to R4 are as defined herein. Such compounds are suitable for use in the treatment or prevention of diseases or conditions which are mediated by the activation of lactate dehydrogenase A (LDHA), for example cancer.