The disclosure describes a method for improving cerebrospinal fluid flow and improving functions of the blood-cerebrospinal fluid barrier by restoring its capacity to filter toxins into cerebrospinal fluid. In some examples, the method includes accessing a cisterna magna space and withdrawing a volume of cerebrospinal fluid from the cisterna magna space. After withdrawal, the same volume of cerebrospinal fluid is infused back into the cisterna magna space to exert pressure, which is transmitted as kinetic energy to the membrane of the blood-CSF barrier. This re-establishes the membrane with a proper electrochemical potential difference such that normal filtration mechanisms resumes with ongoing CSF production.
