Acharya, Raksha,Burnett, Duane A.,Bursavich, Matthew Gregory,Cook, Andrew Simon,Harrison, Bryce Alden,Koenig, Gerhard,McRiner, Andrew J.
申请号:
AU2015362790
公开号:
AU2015362790A1
申请日:
2015.12.14
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention relates to novel geminal substituted quinuclidine amide compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of α7- nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.