POSTACIE KRYSTALICZNE SOLI CHLOROWODORKOWEJ (4A-R,9A-S)-1-(1H-BENZOIMIDAZOLO-5-KARBONYLO)-2,3,4,4A,9,9A-HEKSAHYDRO-1H-INDENO[2,1-B]PIRYDYNO-6-KARBONITRYLU I ICH ZASTOSOWANIE JAKO INHIBITORY HSD 1

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专利权人:

Boehringer Ingelheim International GmbH

发明人:

ECKHARDT, MATTHIAS,MARTIN, HANS-JUERGEN,SCHUEHLE, MARTIN,SICK, SANDRA,YANG, BING-SHIOU

申请号：

PL11785232

公开号：

PL2635563T3

申请日:

2011.11.04

申请国别(地区):

PL

年份:

2015

代理人:

摘要：

The present invention relates to compounds defined by formula I wherein the variables R1, R2, R3, R4, and m are defined as in claim 1, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of 11&bgr；-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity, and dyslipidemia.

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