New combination between 4-{ 3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy} benzamide and an nmda receptor antagonist, and pharmaceutical compositions containing it

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专利权人:

LES LABORATOIRES SERVIER

发明人:

SORS AURORE,TROCME-THIBIERGE CARYN,MERDES ANNETTE

申请号：

NZ60408412

公开号：

NZ604084A

申请日:

2012.12.06

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

Disclosed herein is a combination of 4-{ 3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]benzamide, particularly in the form of an oxalate or hydrochloride and an NMDA glutamatergic receptor antagonist, particularly memantine and more particularly in the form of an hydrochloride, and the use therof in the treatment of cognitive disturbances associated with cerebral aging and with neurodegenerative disease, such as Alzheimer&rsquo；s disease.

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