Fuwai Hospital; Chinese Academy of Medical Sciences and Peking Union Medical College
发明人:
Yuejin Yang,Peisen Huang,Guihao Chen
申请号：
US16833405
公开号：
US20200224169A1
申请日:
2020.03.27
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method for preparing mesenchymal stem cell-derived exosomes on the basis of drug pretreatment, the method for preparing mesenchymal stem cell-derived exosomes comprising: using a statin to pretreat mesenchymal stem cells, and culturing the treated mesenchymal stem cells to collect exosomes secreted thereby. Also provided is an application of a statin in preparing a preparation for promoting the anti-apoptotic abilities and/or homing abilities of mesenchymal stem cells； and further provided is an application of a statin in preparing a preparation for promoting mesenchymal stem cells to secrete exosomes having myocardial infarction microenvironment-improving effects and/or myocardial repair abilities.
