An equine medicinal delivery system includes a dental roll impregnated with a medicinal solution for placement in an equine hoof. Another embodiment of an equine medicinal delivery system includes a pledget impregnated with a medicinal solution for placement in an equine hoof. A method of manufacturing an equine medicinal delivery system includes providing copper sulfate powder, combining water with the copper sulfate power to form a solution, and impregnating an applicator device with the solution. A method of manufacturing an equine medicinal delivery system includes providing an applicator device impregnated with a medicinal solution for placement in an equine hoof.