#$%^&*AU2019206076A120190808.pdf#####ABSTRACT The present invention describes combination treatment comprising a PD-i axis binding antagonist and a MEK inhibitor and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer. 11278215_1 (GHMatters) P93275.AU.38/15 E 0) cy0 0)0 o)o o a 0 a o WI) 0 L IN EELOEE E E EO CI 0 a a- c'J0 im 10 LoD r06 06 06 C6C 6C 6 o - F- 0-F -F- l l CoC