A method and device for measuring biological status parameters are provided. The method includes the following steps: during a predetermined constant period, applying a predetermined specific voltage to a biological specimen to be examined and obtaining a first current during a predetermined vary period, applying a predetermined varying voltage to the biological specimen and obtaining a second current calculating a blood biochemical index according to the first and second currents. The predetermined varying voltage has a predetermined varying frequency and predetermined varying amplitude.本發明係揭露一種生物參數量測方法及其裝置,生物參數量測方法可包含下列步驟:在預設固定時間區間,對待測生物檢體施加預設特定電壓,並取得第一量測電流值;在預設變化時間區間,對待測生物檢體施加預設變化電壓,並取得第二量測電流值;依據第一量測電流值與第二量測電流值而估算血液生化指標值。其中,預設變化電壓可具有預設變化頻率與預設變化振幅。S11、S13、S14‧‧‧步驟
