Ye Yuan;Lee D. Spate;R. Michael Roberts;Randall S. Prather
发明人:
Ye Yuan,Lee D. Spate,Randall S. Prather,R. Michael Roberts
申请号：
US15445621
公开号：
US20170258495A1
申请日:
2017.02.28
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides a novel oocyte maturation medium or/and embryo culture medium with a chemically defined supplement to produce matured oocytes at high efficiency. The inventive medium or supplement comprises three growth factors, namely, fibroblast growth factor 2 (FGF2), leukemia inhibitory factor (LIF), and insulin-like growth factor 1 (IGF-1) in a synergistic combination. Methods for oocyte and embryo culture are also provided.
