Nicholas Maxwell Fisk,Ernst Jurgen Wolvetang,Rebecca Anne Pelekanos
申请号：
US13575493
公开号：
US20130084267A1
申请日:
2011.01.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates generally to a method for generating mesenchymal stem cells from pluripotent cells, the method comprising (i) differentiating a population of pluripotent stem cells in the presence of an inhibitor of endogenous activin and TGF-β signalling and (ii) passaging the cells differentiated in step (i) in the presence of a mesenchymal stem cell medium for a time and under conditions sufficient to produce mesenchymal stem cells. The present invention also relates to mesenchymal stem cells produced by the methods of the present invention and uses thereof.
