PARK, CHAN HEE,朴瓒熙,朴瓚熙,IM, JUN HWAN,任峻桓,LEE, SOON OK,李顺玉,李順玉,LEE, SANG HWI,李尚徽,KO, KWANG SEOK,高广硕,高廣碩,KIM, BYUNG HO,金炳昊,MOON, HYUNG JO,文炯朝,KIM,JAE ILL,金在一,PARK, HEON KYU,朴宪奎,朴憲奎,HO
申请号：
TW108118755
公开号：
TW202016076A
申请日:
2019.05.30
申请国别(地区):
TW
年份:
2020
代理人:
摘要：
The present invention relates to novel heterocyclic compounds useful in preparing drugs for the prevention or treatment of diseases associated with STAT3 protein. Specifically, these drugs are useful in the prevention or treatment of solid tumors, blood cancers, radiation or drug-resistant cancers, metastatic cancers, inflammatory diseases, immune system diseases, diabetes, macular degeneration, papillomavirus infections and tuberculosis.本發明係有關於可用於製造與STAT3蛋白質相關疾病之預防或治療用藥物的新穎雜環化合物。特定言之，此等藥物可用於實體腫瘤、血癌、放射線抗性或藥物抗性癌、轉移癌、發炎性疾病、免疫系統疾病、糖尿病、黃斑部退化、乳突瘤病毒感染、及結核病之預防或治療。
