Disclosed is a benzylpiperizine compound represented by formula (1) or a pharmaceutically acceptable salt thereof, which is useful as a medicinal agent such as an antidepressant agent. (In the formula (1), R 1 represents a hydrogen atom or a methyl group R 2 is a group bound in a p- or m-position relative to a methylene group and represents a chlorine atom bound in a p-position, a bromine atom bound in a p-position, a methyl group bound in a p-position, a chlorine atom bound in a m-position or a bromine atom bound to in a m-position X represents a methylene or an oxygen atom and n represents an integer of 1 to 3.)本發明乃下式(1)所示苄基哌啶化合物,或其藥學上可容許之鹽有關:「式中,R1示氫原子或甲基,R2乃對於伸甲基呈對位或間位而結合之基,示對位結合之氯原子、對位結合之溴原子、對位結合之甲基、間位結合之氯原子或間位結合之溴原子、X示伸甲基或氧原子,n示1~3之整數。」本發明化合物可提供抗鬱劑等醫藥用途。
