Described herein are methods for neuromodulating brain activity of one or more target brain regions, the methods using Transcranial Magnetic Stimulation (TMS) to produce robust analgesia. In particular, described herein are systems for arranging one or more (e.g., a plurality) of TMS electromagnets oriented in a transverse direction, perpendicular to the posterior-anterior axis of the head, and applying sufficient energy to neuromodulate the target deep brain region.
