Brushite (DCPD, dicalcium phosphate dihydrate, CaHPO4-2HH2O) and octacaicium phosphate (OCP, Ca8(HPO4)2(PO4)4-5H2O) granules in the millimetre size range were prepared by using calcium carbonate granules of marble-origin as the starting material. The method of the invention comprised of soaking the marble granules in aqueous solutions containing phosphate and/or calcium ions at temperatures between 20° and 75° C. The load-bearing DCPD and OCP granules of this invention are useful in maxillofacial and orthopedic void/bone defect filiing and grafting applications.
