MILNE, JILL C.,JIROUSEK, MICHAEL R.,BEMIS, JEAN E.,SMITH, JESSE J.
申请号：
CA2729186
公开号：
CA2729186C
申请日:
2009.07.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The invention relates to Fatty Acid Acetylated Salicylate Derivatives having astructureof Formula I: or pharmaceuticallyacceptable salts, hydrates, solvates, prodrugs, enantiomers, and stereoisomersthereof, whereinR1, R2, R3, R4, W1,W2,-----, a, b, c, d, n, o, p, q, t, Z and Q are as definedherein. This inventionalso relates to Fatty Acid Acetylated Salicylate Derivatives having astructure of Formula III:or pharmaceutically acceptable salts, hydrates, solvates, prodrugs,enantiomers, andstereoisomers thereof, wherein W1, W2,-----, a, b, c, d, n, o, p, q, t, u, Z,Q and R are asdefined herein. Compositions comprising an effective amount of such compounds,and methodsfor treating or preventing an inflammatory disorder comprising theadministration of an effectiveamount of such compounds are also provided.
