Fundação de Amparo à Pesquisa do Estado de Minas Gerais - Fapemig
发明人:
SALCEDO, Joaquín Hernán Patarroyo,VILÓRIA, Marlene Isabel Vargas,SOSSAL, Sidimar,DE ARAÚJO, Leandro Silva,GOMEZ, Gabriel Andrés Tafur,MENDES, Márcio Alberto Dias
申请号：
EP14854077
公开号：
EP3059313A4
申请日:
2014.10.15
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention relates to the field of biotechnology and genetic engineering, and particularly to the expression of recombinant peptides. The inoculation thereof in cattle results in the production of an immune response capable of adversely affecting Rhipicephalus microplus ticks, which feed on the inoculated cattle, decreasing the number and reproductive capacity of this tick species. Such recombinant immunogen can be used as an effective vaccine for tick control. The technical goal is the design and construction of two synthetic genes made with preferred codons for Pichia pastoris and expression thereof from a recombinant peptide, which consists in a continuous sequence and of a recombinant peptide, respectively, and the drug composition based of said recombinant polypeptide.
