The present disclosure provides pharmaceutical compositions of statins and polyunsaturated fatty acids (PUFAs), in which the statins are dissolved in the PUFAs, the PUFA species being present substantially in the free acid form. Also provided are oral unit dosage forms of the disclosed pharmaceutical compositions and methods of treating blood lipid disorders using the compositions and oral unit dosage forms.本揭示提供史他汀及多不飽和脂肪酸(PUFA)之醫藥組合物,其中該等史他汀溶於PUFA中,PUFA物質實質上呈自由酸形式存在。亦提供所揭示之醫藥組合物的口服單位劑型,及利用該等組合物及口服單位劑型治療血脂異常的方法。