IDENTIFICATION DE LYMPHOCYTES CD8+ QUI ONT UNE EXPRESSION ELEVEE DE CD161 (CD161HI) ET/OU DE IL18R?(ALPHA) (IL18R?(ALPHA)HI) ET QUI ONT UNE CAPACITE D'ECOULEMENT DE MEDICAMENT RAPIDE
This invention provides, among other things, methods for the identificationand isolation of viable putativelong-lived antigen-specific memory CD8+ T cell subsets (CMhi and EMhi) withhigh surface expression of CD161 and/or IL-18R.alpha. andthe capacity to rapidly efflux the fluorescent dye Rh123.