FREIDMAN, DORON,BESONOV, ALEX,TAMAKRIN, DOV,EINI, MEIR
申请号:
CA2606933
公开号:
CA2606933C
申请日:
2006.04.18
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
A composition and therapeutic kit including an aerosol packagingassembly including:a container accommodating a pressurized product; andan outlet capable of releasing the pressurized product as a foam;wherein the pressurized product comprises a foamable composition including:i. a steroid;ii. at least one organic carrier selected from the group consisting of ahydrophobic organic carrier, a polar solvent, an emollient and mixturesthereof, ata concentration of about 2% to about 50% by weight;iii. a surface-active agent;iv. about 0.01% to about 5% by weight of at least one polymeric additiveselected from the group consisting of a bioadhesive agent, a gelling agent, afilmforming agent and a phase change agent;v. water; andvi. liquefied or compressed gas propellant at a concentration of about 3%to about 25% by weight of the total composition.The composition further may include a therapeutically active foam adjuvant,selected from the group consisting of a fatty alcohol, a fatty acid, ahydroxyl fattyacid; and mixtures thereof.