SON, HOE JOOKR,손회주,PARK, YONG KYUKR,박용규,KIM, YOUNG TAEGKR,김영택,OH, DO YEONKR,오도연,KIM, JUNG HEEKR,김정희,JO, BOUNG SUNKR,조병선
申请号：
KR1020130064010
公开号：
KR1020140142789A
申请日:
2013.06.04
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
Provided in the present invention are an intermediate compound useful in preparing Gefitinib and a method for preparing the same. The intermediate compound is used to prepare high purity high yield Gefitinib. The method for preparing compound of chemical formula 7 comprises the steps of: a) preparing a compound of chemical formula 6 by reducing a compound of following chemical formula 5 and b) cyclizying the compound of chemical fomula 6 and unsatureated six-atom heterocycle compound with an organic base in presence of alcohol solvent having one to four carbon atoms to preparing a compound of chemical formula 7.COPYRIGHT KIPO 2015본 발명은 게피티닙을 제조하는데 유용한 중간체 화합물 및 그의 제조방법을 제공하며, 본 발명의 중간체 화합물을 사용하여 고순도, 고수율의 게피티닙을 제조할 수 있다.
