THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;ARAVIVE BIOLOGICS, INC.
发明人:
Amato J. GIACCIA,Erinn Bruno RANKIN,Jennifer R. COCHRAN,Douglas JONES,Mihalis KARIOLIS,Katherine FUH,Yu MIAO,Susan HERSHENSON
申请号：
HK18115132
公开号：
HK1256071A1
申请日:
2018.11.27
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
Compositions and methods are provided for alleviating cancer in a mammal by administering a therapeutic dose of a pharmaceutical composition that inhibits activity of AXL, MER or Tryo3 protein activity, for example by competitive or non-competitive inhibition of the binding interaction between AXL, MER or Tyro3 and its ligand GAS6.
