isoxazole-thiazole derivatives as an inverse receptor boasts agonist for use in the treatment of cognitive disorders

• 收藏
• 分享

专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

ANDREW THOMAS,MATHEW C. LUCAS,ROLAND JAKOB-ROETNE

申请号：

BRPI1011729

公开号：

BRPI1011729A2

申请日:

2010.04.28

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

The present invention is concerned with isoxazole-thiazole derivatives of formula I, having affinity and selectivity for GABA A &alpha；5 receptor, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/