Provision of [challenges] LXR receptor modulator. Benzenesulfonamide derivative of compound (I), and, A1 The present invention relates to acceptable addition salt thereof in the pharmaceutical formula as defined in the appended claims. The invention also relates to methods for their preparation, compositions Pharmaceutically acceptable they contain, as well as in the treatment nervous tissue-degenerative diseases, cardiovascular diseases, diabetes and hypercholesterolemia and inflammation, the pharmacology of these particular I also relates to the use of the substance as effective. [Formula 1] None [Selection Figure]【課題】LXR受容体モジュレーターの提供。【解決手段】本発明は、特許請求の範囲で定義する一般式(I)のベンゼンスルホンアミド誘導体化合物、及び、その医薬品に許容される付加塩に関する。本発明は、また、これらの調製方法、これらが含む医薬品に許容される組成物、並びに、特に神経組織変性疾患、心血管疾患、炎症及び高コレステロール血症及び糖尿病の治療における、これらの薬理学的有効物質としての使用にも関する。【化1】【選択図】なし