Chunhua Yang,Loic Patrick Le Hir de Fallois,Charles Q. Meng,Alan Long,Roelof Johannes Gorter de Vries,Bruno Baillon,Sylvaine Lafont,Myriam Gay de Saint Michel,Stephane Kozlovic
申请号:
US15480316
公开号:
US10433552B2
申请日:
2017.04.05
申请国别(地区):
US
年份:
2019
代理人:
摘要:
This invention relates to processes for the preparation of antiparasitic isoxazoline compounds enriched in an enantiomer using quinine-based chiral phase transfer catalyst. The invention also relates to novel quinine-based phase transfer catalysts and to a toluene solvent form of the isoxazoline compound of the invention.