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Collagen-based matrix for use as restorative material, and method for preparing the same
专利权人:
Seong-Ki Lee
发明人:
Seong-Ki Lee,Si-Nae Park,Sang-Hee Bae
申请号:
US12423972
公开号:
US08748579B2
申请日:
2009.04.15
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed herein are a collagen-based matrix for use as a restorative material and a method for the preparation thereof. An atelocollagen dispersion is spread at a predetermined thickness over a plate and freeze-dried to form a porous collagen membrane. An atelocollagen dispersion is separately spread over a plate and pressurized to form a dense collagen membrane. This is overlaid with the porous collagen membrane and immersed in an EDS solution in ethanol to crosslink the two membranes with each other. From the bilayer structure thus constructed, EDS is removed, followed by lyophilization and cutting into an appropriate size.
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