A system and method for determining an electrical activity in a subject using ultrasound and electromagnetics are provided. In some aspects, the method includes directing ultrasound energy to a portion of a subject's anatomy using an ultrasound system, wherein the ultrasound energy inducing a perturbation to locations in the subject's anatomy, and sensing, using sensors arranged about the subject, a plurality of electromagnetic signals representing an electrical activity of the subject. The method also includes identifying electromagnetic signals that are modulated by the perturbation, and generating a report of the electrical activity using the identified electromagnetic signals.