Described herein are embodiments of electronic sensorized spherical input and output devices, systems, and methods for capturing gestural input from a user's physical interactions with a spherical device. In one embodiment, the spherical input and output device includes a number of sensors along the surface area of the sphere in a configuration conforming to a user's fingers and hands. A microprocessor receives sensor input and transmits the sensor signals to receiving devices which include computer software to translate the sensor signals to audio output, visual output, or various functions on receiving devices. Additional embodiments of the invention include binary modifier functions which allow the user to trigger a number of different outputs for the sensorized sphere, such as volume control, tempo, sample playback, LED lights, game modes, and other functions. Other embodiments include the integration of inertial measurement units (IMUs), which may include a combination of accelerometers, gyroscopes and magnetometers to capture complex user gestures involving motion, direction and spin of the sensorized sphere to provide unique output signals.