A three-dimensional (3-D) orthopedic drill guide device for accommodating a bone drill during an orthopedic surgery is disclosed. By establishing two specific angles in relation to the bone fascia, the device acts as a guide for bone drilling locations. In one specific instance, it is an optimal 3-D drill guide for the direction and Gamma angle (resulting from the devices Alpha and Beta angles of the device) of a drill hole in a femoral bone when used to replace an injured anterior cruciate ligament (ACL).
